Purpose
The Department of Health and Human Services' Administration for Children & Families oversees the Personal Responsibility Education Innovative Strategies (PREIS) Program. PREIS builds the evidence base for adolescent pregnancy prevention interventions that are effective with high risk and vulnerable youth populations and addresses gaps with new promising program models. The program is designed to support rigorous impact evaluations of innovative youth pregnancy prevention interventions that target youth in foster care/child welfare settings, juvenile justice, victims of trafficking, youth who have runaway or experience homelessness, youth with HIV/AIDS, expectant youth who are under 21 years of age and their partners, parenting youth who are under 21 years of age and their partners, and youth residing in areas with high birth rates for youth.
HHS-2026-ACF-ACYF-AP-0003
Eligible Entities
The following types of organizations are eligible to apply for the grant:
- Independent school districts
- Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
- County governments
- Native American tribal governments (Federally recognized)
- Special district governments
- Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
- City or township governments
- Public and State controlled institutions of higher education
- For profit organizations other than small businesses
- Public housing authorities/Indian housing authorities
- Native American tribal organizations (other than Federally recognized tribal governments)
- Private institutions of higher education
- State governments
- Small businesses
Eligible Activities
Projects must implement at least three of the six congressionally mandated adulthood preparation subjects (APS) which include: 1) healthy relationships, 2) adolescent development, 3) financial literacy, 4) parent-child communication, 5) educational and career success, and 6) healthy life skills. Projects are required to conduct rigorous impact evaluations (randomized controlled trials or quasi-experimental design studies with assignment to treatment or control group). PREIS evaluations must be conducted by an independent, third-party evaluator.
Interventions to be evaluated under this funding opportunity are expected to have compelling, positive preliminary evidence from previous research, but have not been evaluated through a randomized control trial or quasi-experimental design. Interventions must have a well-described theory of change, with intervention materials already developed.
Award
Estimated Total Program Funding: $ 10,000,000
Award Ceiling: $ 900,000
Award Floor: $ 750,000
Estimated Number of Awards: 12
Important Dates
Estimated Open Date: June 19, 2026
Estimated Application Due Date: Jul 21, 2026 (11:59 pm EST)
Estimated Award Date: Aug 14, 2026
Estimated Project Start Date: Sep 30, 2026
Next Steps
If you have difficulty accessing the full announcement, or to learn more, contact Katherine Godesky at 202-401-5525 or fysb.nofo.preis@acf.hhs.gov.